Induction of Oxidative Stress in Rat Brain by Acrylonitrile (ACN)
نویسندگان
چکیده
منابع مشابه
Taurine prevents acrylonitrile-induced oxidative stress in rat brain.
Acrylonitrile (ACN) is a volatile, toxic liquid used as a monomer in the manufacture of synthetic rubber, styrene plastics, acrylic fiber and adhesives. ACN is a potent neurotoxin and a carcinogen, which produces tumors in rats, particularly gliomas of the brain. A role for free radical-mediated lipid peroxidation in the toxicity of ACN has been suggested. We examined the ability of taurine, an...
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Acrylonitrile (ACN) is a volatile, toxic liquid used as a monomer in the manufacture of synthetic rubber, styrene plastics, acrylic fiber, and adhesives. ACN is a potent neurotoxin. A role for free radical mediated lipid peroxidation in the toxicity of ACN has been suggested. We examined the ability of hesperidin, an antioxidant flavonoid, to attenuate ACN-induced alterations in lipid peroxidat...
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ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 1998
ISSN: 1096-6080
DOI: 10.1006/toxs.1998.2524